β-Casomorphin, bovine TFA

CAS No. ——

β-Casomorphin, bovine TFA( β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA )

Catalog No. M29705 CAS No. ——

β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    β-Casomorphin, bovine TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
  • Description
    β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.(In Vitro):β-Casomorphin, bovine TFA (0.1μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment. β-Casomorphin, bovine TFA (0.1μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels. β-Casomorphin, bovine TFA does not modify the expression of rMuc1, rMuc4, and rMuc5AC. β-Casomorphin, bovine TFA (0.1μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).(In Vivo):β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats. β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats. β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats. β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IC50: 14 μM (Opioid receptor)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    903.94
  • Molecular Formula
    C43H56F3N7O11
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:Tyr-Pro-Phe-Pro-Gly-Pro-Ile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Brantl V, et al. Opioid activities of beta-casomorphins. Life Sci. 1981 Apr 27;28(17):1903-9.
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